Toxicity of lunar dust assessed in inhalation-exposed rats

Humans will again set foot on the moon. The moon is covered by a layer of fine dust, which can pose a respiratory hazard. We investigated the pulmonary toxicity of lunar dust in rats exposed to 0, 2.1, 6.8, 20.8 and 60.6 mg/m(3) of respirable-size lunar dust for 4 weeks (6 h/day, 5 days/week); the aerosols in the nose-only exposure chambers were generated from a jet-mill …

Apigenin protects against bleomycin‑induced lung fibrosis ...

Apigenin is a non‑toxic and non‑mutagenic flavone that exists abundantly in numerous herbs and vegetables. Apigenin exerts anti‑proliferative and anti‑inflammatory properties. The aim of the present study was to investigate the effects of apigenin on bleomycin‑induced lung fibrosis in rats. A single intratracheal instillation of bleomycin (5 …

Effective-components combination improves airway ...

Compared to the Normal rats, the lung tissues in the Model rats showed severe pathological injuries, including increased mean linear intercept, increased mean small airway wall thickness, and decreased mean alveolar number (Fig. 1d–h). These changes in the ECC and APL-treated rats were obviously ameliorated.

Decellularized Rat Lung Scaffolds Using Sodium Lauryl ...

Rat lungs were harvested as previously described. 13 In brief, the rats were injected intraperitoneally with pentobarbital sodium (140 mg/kg, Sigma-Aldrich, St. Louis, MO) for anesthesia and heparin (250 U/kg, Sigma) for anticoagulation. Immediately after euthanasia, the intact heart-lung blocs were removed and stored at −80°C until used.

Evaluation of polyhexamethylene guanidine-induced lung ...

At 4- and 8-weeks post-instillation, one lobe of the right lung from 3 rats was subjected to RNA sequencing. At least one abnormal CT finding was found in all rats at all weeks. The major CT ...

Mill Rats: When The Boys Got In Trouble She Always Go Them ...

Knowledge of English is determined not only by pure pronunciation. Often, even students are asked to write a short essay or story in order to determine the level Mill Rats: When The Boys Got In Trouble She Always Go Them Out But Smuggling Refugees Is A Whole New Game of proficiency in written English. But what if talking is easy, but writing is difficult.

Johnstown Mill Rats (@Mill_Rats) | Twitter

The latest Tweets from Johnstown Mill Rats (@Mill_Rats). • The Official Twitter Page of the Johnstown Mill Rats • Proud member, @ProspectLeague • #RatPack • Best Friends, @66ersbaseball, @discoturkeys •. Johnstown, PA

Pyrrolidine Dithiocarbamate Attenuates Paraquat-Induced ...

Paraquat (PQ) has been demonstrated that the main target organ for the toxicity is the lung. This study aimed to investigate the potential protective effect of PDTC on the PQ-induced pulmonary damage. Fifty-four rats were divided into control, PQ-treated and PQ+PDTC-treated groups. Rats in the PQ group were administrated 40 mg/kg PQ by gastric gavage, and PDTC group with …

Ferroptosis is involved in hyperoxic lung injury | JIR

Rats in both groups were deeply anesthetized with isoflurane after seven days of modeling and saced. Lung tissues were quickly removed, and RIPA lysis buffer (Beyotime, China) and protease inhibitors were added. The supernatant was collected after centrifugation at 12,000 g, 4°C for 10 min.

Collection of RAT items | What word relates to all three ...

The Remote Associates Test (RAT) is a test of creative potential. It was developed by Martha Mednick in 1962 and has since been considered as a valid measure of creativity. Creativity is an aspect of personality, more specifically the trait of Openness to experience from the Big Five Personality model. Another great test to measure your ...

Rat Lungworm Disease and How to Prevent It

Rat lungworm is a parasitic roundworm known by the scientific name Angiostrongylus cantonensis. Rats are the primary hosts for this parasite and the only animal in which the worm can complete its full life cycle. When humans are infected with rat lungworm, the parasite can't fully mature or reproduce.

What You Need To Know About Rat Lungworm Disease - …

Rat lung worm or Angiostrongylus cantonensis is a parasite that mainly lives in rodents such as rats and can infect snails and slugs that come into contact with infected rat faeces. People can be infected when they eat an infected snail or slug or even the slime that they leave behind. What are the symptoms? Most people may have no symptoms at all.

Implantation of fetal rat lung fragments into bleomycin ...

Fetal rat lung fragments could survive and differentiate in bleomycin-induced completely fibrotic lung. Implantation of fetal rat lung fragments into bleomycin-induced pulmonary fibrosis J Thorac Cardiovasc Surg. 2012 Jun;143(6):1429-35. doi: 10.1016/j.jtcvs.2012.01.002. ...

Rat Lungworm: What You Need To Know - Malama O Puna

Animals can also get rat lungworm. A sloth at the Hilo Zoo got rat lungworm and became paralyzed in the hind legs. There have been reports of people's cats and horses contacting it. To avoid ingestion of a slug or slug slime look closely (put on your glasses if you wear them) and thoroughly wash all vegetables and fruit under running water.

DISSOLUTION OF GLASS FIBERS IN THE RAT LUNG …

9/7/2017 DISSOLUTION OF GLASS FIBERS IN THE RAT LUNG FOLLOWING INTRATRACHEAL INSTILLATION ... Slices approximately 50 µm thick were cut from the blocks with a rotary end mill, and, after removing the resin by low temperature ashing, the fibers were collected and mixed to ensure homogeneity. The average lengths of these

Characteristic gene expression profiles in the progression ...

A rat model of liver cancer induced by diethylnitrosamine was established. The cirrhotic tissue, the dysplasia nodules, the early cancerous nodules and the cancerous nodules from the rats with lung metastasis were chosen to compare with liver tissue of normal rats to investigate the differential expression genes between them.

Transcriptomic Analysis Exploring the Molecular Mechanisms ...

Histopathological changes in rat lung. H&E staining of lung tissues in (a) control group, (b) model group, and (c) HCZP group at magnification × 400. (d) The values of total wall thickness (WAt/Pbm), inner wall thickness (WAi/Pbm), and smooth muscle layer thickness (WAm/Pbm) in three groups. Data are expressed as the mean ± SD (n = 10).

The Truth About Rat Lungworm Disease - Hawai'i ...

Rat lungworm is a form of parasitic worm. According to the Centers of Disease Control and Prevention (CDC), the adult parasite is found in rats, which pass the larvae of the parasite in their droppings. When the waste is eaten by snails and slugs, the larvae are ingested.

Lung injury and expression of p53 and p16 in Wistar rats ...

The lung tissue of the Wistar rats exposed to chrysotile from the four mining areas was shown that its appearance and the difference of lung function were significant (P < 0.05). HE staining showed that four kinds of chrysotile fiber damaged the lung tissue in different degrees, and long-term exposure could induce lung fibrosis (Table 2, Fig ...

Isolation and characterization of rat primary lung cells ...

Lung cell culture may be useful as anin vitro alternative to study the susceptibility of the lung to various toxic agents. Lungs from Wistar rats were enzymatically digested by recirculating perfusion through the pulmonary artery with a sequence of solutions containing deoxyribonuclease, chymopapain, pronase, collagenase, and elastase. Lung tissue was …

Observations on the Heart-Lung Preparation in the Rat

output with a device resembling a water mill. Malinow and associates6 described a technique of preparing the rat heart-lung, but reported no observations upon it. Pietra an7 d Minelli also described a technique, and measured flow with a mechanical drop counter. Solomon and associates8-9 developed a technique for pre-

Alveolar collapse of rat lung - YouTube

I don't know who did this video. I just know it's a mechanically ventilated rat with its chest opened and the pleura removed. 5x slow collapse.

Adipose-derived mesenchymal stem cells attenuate acute ...

ADMSCs can improve the 24-h survival rate of rats, reduce lung injury, and reduce TNF-α and IL-6 serum levels. The cecum of CLP-induced sepsis rats was congested and necrotic, while the cecum of rats from the CLP-ADMSCs group was significantly improved (Fig. S1, macroscopic view of the rat model).In addition, the 24-h mortality rates of the SC group, …

Research Article Sequential Treatments with Tongsai and ...

Lung Tissue Sectioning and Bronchoalveolar Lavaging. All animals were sacri ced by exsanguination of the abdom-inal aorta a er blood was collected. e trachea was can-nulated, and the heart/lung block was removed from the thoracic cavity. e right extrapulmonary bronchus was ligated with sutures, and the right lung lobes were removed. e / ()= / .

The Quietus | Features | Noel's Straight Hedge | Straight ...

The self-titled debut release (there's a song on a comp tape from earlier this year if you want to be a real stickler) by Unidad Ideológica from Bogotá, Colombia calls itself an LP too but runs about as long as the above release… and proper wallops you the entire time. Anyone emerging from the other side of its desperate, distortion-devastated barrage wanting more …

Protection Against Radiation-Induced Duox1 and Duox2 ...

The results of IL4Ra1 gene expression showed that when rats' lung tissues received irradiation by gamma rays, the expression of this gene increased by 5.94 ± 1.74 fold compared to the control group (P < 0.05). When rats were treated with a combination of curcumin and L-selenomethionine, the expression of IL4Ra1 was reduced by 2.21 ± 0.59 ...

Evaluation of the Oxidative Effect of Long-Term Repetitive ...

Hyperbaric oxygen (HBO2) exposure affects both oxidative and antioxidant systems. This effect is positively correlated with the exposure time and duration of the treatment. The present study aims enlightening the relation of HBO2 with oxidative/antioxidant systems when administered in a prolonged and repetitive manner in brain tissues of rats. Sixty …

Hypersensitivity Pneumonitis and Related Conditions in the ...

lung Mill workers Wheat flour (contaminated) Sitophilus (wheat weevil) Wheat weevil disease Malt workers Moldy brewing malta Malt worker's lung Soy sauce brewer Soy sauce production Aspergillus oryzae Laboratory workers Laboratory reagent Pauli reagent Pauli HP Rodentsa Rat or gerbil urinary proteins Gerbil keeper's lung Textile/clothing ...

Intoxicating Facts About Dean Martin, The King Of Cool

Intoxicating Facts About Dean Martin, The King Of Cool. Dean Martin was one of a kind. The child of working-class Italian immigrants, this shy, stammering boy grew up to be a boxer, a comedian, a singer, an actor, and everything in …

Angiostrongyliasis (Rat Lungworm) | Disease Outbreak ...

About This Disease Angiostrongyliasis, also known as rat lungworm, is a disease that affects the brain and spinal cord. It is caused by a parasitic nematode (roundworm parasite) called Angiostrongylus cantonensis. The adult form of A. …